Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 4/20 | 0.34 |
| ▸ | FNTB | P49356 | 4/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975970 | 0.92 | HTR6 (0.39) | CHEK1CYP2C19ACP1EED | |
| SCHEMBL7990500 | 0.91 | KDM1A (0.41) | CHEK1KDM1ASCN9A | |
| SCHEMBL7505916 | 0.89 | CCNT1 (0.38) | KDM1A | |
| SCHEMBL7994923 | 0.89 | PRKCA (0.40) | CHEK1CYP2C19ACP1EED | |
| SCHEMBL7975983 | 0.89 | CCNT1 (0.36) | KDM1AFNTAFNTB | |
| SCHEMBL7976272 | 0.89 | CCNT1 (0.41) | CHEK1CYP2C19ACP1EED | |
| SCHEMBL7990448 | 0.86 | CYP11B1 (0.40) | ACP1 | |
| SCHEMBL7993914 | 0.86 | HTR6 (0.38) | EED | |
| SCHEMBL7994416 | 0.85 | CCNT1 (0.37) | KDM1A | |
| SCHEMBL7987194 | 0.84 | HTR6 (0.37) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265403-B1 | TYROSINE INHIBITORS | MERCK & CO., INC. | 2001-07-24 | — | — | US | disclosed |