Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975992 | 0.97 | LMNA (0.47) | LMNAMAPTCA1CA2ELANE | |
| SCHEMBL7064562 | 0.92 | LMNA (0.49) | LMNAMAPTCA1CA2ELANE | |
| SCHEMBL7976230 | 0.92 | CTRC (0.38) | LMNACA1CA2ELANECTRC | |
| SCHEMBL7973259 | 0.90 | FKBP1A (0.43) | LMNAMAPTCA1CA2FKBP1A | |
| SCHEMBL7969990 | 0.89 | ALDH1A1 (0.38) | LMNACA1CA2ELANECTRC | |
| SCHEMBL7971248 | 0.87 | FKBP1A (0.41) | LMNAMAPTCA1CA2FKBP1A | |
| SCHEMBL7976224 | 0.86 | KMT2A (0.42) | LMNAMAPTCA1CA2HPGD | |
| SCHEMBL7976100 | 0.86 | CYP24A1 (0.37) | LMNAFKBP1A | |
| SCHEMBL7441323 | 0.85 | LMNA (0.51) | LMNAMAPTCA1CA2ELANE | |
| SCHEMBL7975853 | 0.84 | PSMD10 (0.43) | MAPTCA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |