Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979658 | 1.00 | HTR1A (0.42) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL8196333 | 0.88 | ADRB2 (0.36) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL8196331 | 0.88 | ADRB2 (0.36) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL8195910 | 0.87 | HRH4 (0.36) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL8195916 | 0.87 | HRH4 (0.36) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL8199078 | 0.79 | HTR1A (0.42) | HTR1AADRA1DADRA1AADRA1BHTT | |
| SCHEMBL7982471 | 0.78 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3SIGMAR1ADRB2 | |
| SCHEMBL7982467 | 0.78 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3SIGMAR1ADRB2 | |
| SCHEMBL8919392 | 0.78 | HRH4 (0.48) | ADRB2ADRB1ADRB3 | |
| SCHEMBL7976352 | 0.77 | KCNA3 (0.42) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |