Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 9/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982357 | 1.00 | BCHE (0.41) | BCHEHPGDSCHRM2HTR1AADRA2A | |
| SCHEMBL7976349 | 0.88 | KCNA3 (0.42) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7976352 | 0.88 | KCNA3 (0.42) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7979784 | 0.85 | MGLL (0.37) | SLC6A2ADRA1ASLC6A3ADRA1DADRA1B | |
| SCHEMBL7977968 | 0.84 | SLC6A2 (0.36) | SLC6A2ADRA1ASLC6A3ADRA1DADRA1B | |
| SCHEMBL7977969 | 0.84 | SLC6A2 (0.36) | SLC6A2ADRA1ASLC6A3ADRA1DADRA1B | |
| SCHEMBL7982371 | 0.82 | CA1 (0.42) | DRD3LMNADRD2 | |
| SCHEMBL7982369 | 0.82 | CA1 (0.42) | DRD3LMNADRD2 | |
| SCHEMBL8187857 | 0.82 | BCHE (0.45) | BCHEHPGDSCHRM2HTR1AADRA2A | |
| SCHEMBL7982482 | 0.77 | DRD2 (0.46) | DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |
| US-10308734-B2 | Catalyst components for the polymerization of olefins and catalysts therefrom obtained | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2019-06-04 | — | — | US | disclosed |
| US-20150259443-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS AND CATALYSTS THEREFROM OBTAINED | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2015-09-17 | — | — | US | disclosed |
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000076981-A1 | PIPERIDINYL AND PIPERAZINYL SUBSTITUTED BENZOFUSED LACTAMS | NEUROGEN CORPORATION (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |