SCHEMBL6032704

SCHEMBL6032704

CC(=O)ON1C(C)(C)CC(CCCCNc2nc(Cl)nc(Cl)n2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976903 0.85 KMT2A (0.37) KMT2A
SCHEMBL7458930 0.82 KMT2A (0.40) KMT2A
SCHEMBL692772 0.82 KMT2A (0.40) KMT2A
SCHEMBL9428396 0.81 KMT2A (0.42) KMT2A
SCHEMBL1139271 0.81 TSHR (0.34) TSHR
SCHEMBL6300705 0.81 KMT2A (0.36) KMT2A
SCHEMBL698650 0.81 KMT2A (0.40) KMT2A
SCHEMBL1892389 0.80 KMT2A (0.44) KMT2A
SCHEMBL2022080 0.80 KMT2A (0.45) KMT2A
SCHEMBL524341 0.79 KMT2A (0.33) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050239927-A1 Dyeable polyolefin fibers and fabrics LEGGIO ANDREW J 2005-10-27 US claimed
CN-111406061-A Stabilized polyolefin compositions comprising benzofuranones and acid scavengers 巴斯夫欧洲公司 2020-07-10 CN disclosed
CN-111051322-A Stabilized polyolefin compositions comprising benzofuranones and organophosphorus stabilizers 巴斯夫欧洲公司 2020-04-21 CN disclosed
US-7084197-B2 Synergistic combinations of nano-scaled fillers and hindered amine light stabilizers CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-08-01 US disclosed
US-20050239927-A1 Dyeable polyolefin fibers and fabrics LEGGIO ANDREW J 2005-10-27 US disclosed
US-20050004294-A1 Synergistic combinations of nano-scaled fillers and hindered amine light stabilizers CIBA SPECIALTY CHEMICALS CORP. 2005-01-06 US disclosed
EP-1401947-A1 SYNERGISTIC COMBINATIONS OF NANO-SCALED FILLERS AND HINDERED AMINE LIGHT STABILIZERS Ciba SC Holding AG (CH) 2004-03-31 EP disclosed
WO-2003002651-A1 SYNERGISTIC COMBINATIONS OF NANO-SCALED FILLERS AND HINDERED AMINE LIGHT STABILIZERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-01-09 WO disclosed