Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.46 |
| ▸ | CA1 | P00915 | 16/20 | 0.46 |
| ▸ | CA9 | Q16790 | 14/20 | 0.46 |
| ▸ | CA12 | O43570 | 13/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 7/20 | 0.42 |
| ▸ | CA6 | P23280 | 3/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202948 | 0.67 | CA2 (0.81) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL7976910 | 0.67 | CA2 (0.47) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL2771870 | 0.66 | CA2 (0.56) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL5722180 | 0.66 | ALDH1A1 (0.66) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL9097181 | 0.64 | LMNA (0.70) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL5487533 | 0.64 | CHRNA7 (0.49) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL18118187 | 0.64 | LMNA (0.70) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL8299104 | 0.64 | CA1 (0.86) | CA2CA1CA9CA12ALDH1A1 | |
| Benzenesulfonamide SCHEMBL3603399 | 0.64 | CA1 (0.59) | CA2CA1CA9CA12CA7 | |
| SCHEMBL7973334 | 0.63 | CA2 (0.44) | CA2CA1CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001014368-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING INFLUENZA | VIROPHARMA INCORPORATED (US) | 2001-03-01 | — | — | WO | claimed |