Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975405 | 0.92 | MAPT (0.54) | LMNAMEN1MAPTKMT2ANPC1 | |
| SCHEMBL7977571 | 0.91 | NPC1 (0.53) | LMNAKMT2ANPC1RAB9ARECQL | |
| SCHEMBL7975349 | 0.88 | CYP1A2 (0.51) | LMNAPKMNPC1RAB9ACYP1A2 | |
| SCHEMBL7980389 | 0.88 | NPC1 (0.49) | LMNAMAPTKMT2ANPC1RAB9A | |
| SCHEMBL7980306 | 0.86 | NPSR1 (0.49) | NPC1RAB9ACYP1A2CYP2D6TSHR | |
| SCHEMBL7974403 | 0.85 | RAB9A (0.47) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL7974413 | 0.85 | SMN1; SMN2 (0.59) | LMNANPC1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL7977564 | 0.85 | POLB (0.50) | LMNAKMT2ANPC1RAB9AMPO | |
| SCHEMBL7980161 | 0.85 | RAB9A (0.50) | LMNAMEN1MAPTKMT2ANPC1 | |
| SCHEMBL7974288 | 0.84 | KMT2A (0.65) | LMNAMEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |