Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977544 | 0.86 | LMNA (0.57) | CYP1A2CYP2C19CYP2D6TSHRNPC1 | |
| SCHEMBL7980389 | 0.85 | NPC1 (0.49) | NPSR1POLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL7964005 | 0.84 | POLB (0.46) | NPSR1POLBPTGS2NPC1RAB9A | |
| SCHEMBL7974413 | 0.84 | SMN1; SMN2 (0.59) | POLBCYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL7977571 | 0.84 | NPC1 (0.53) | POLBNPC1RAB9AMPO | |
| SCHEMBL7975349 | 0.83 | CYP1A2 (0.51) | NPSR1POLBCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL7975303 | 0.83 | MPO (0.58) | NPSR1POLBMPOGAA | |
| SCHEMBL7977564 | 0.82 | POLB (0.50) | NPSR1POLBNPC1RAB9AMPO | |
| SCHEMBL7975405 | 0.82 | MAPT (0.54) | NPC1RAB9AGAA | |
| SCHEMBL7977587 | 0.82 | NPC1 (0.58) | POLBNPC1RAB9AMPOTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | claimed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |