Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418263 | 0.88 | MCHR1 (0.49) | MCHR1 | |
| SCHEMBL7967629 | 0.83 | MAPT (0.55) | L3MBTL1MAPTMCHR1KITLMNA | |
| SCHEMBL7980655 | 0.81 | ADRB3 (0.44) | — | |
| SCHEMBL7980659 | 0.79 | HTR1D (0.36) | KIT | |
| SCHEMBL7980657 | 0.78 | HTR1D (0.35) | KIT | |
| SCHEMBL7111545 | 0.77 | MTNR1A (0.57) | — | |
| SCHEMBL7110432 | 0.76 | L3MBTL1 (0.60) | L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5197720 | 0.75 | L3MBTL1 (0.59) | L3MBTL1MAPTKITLMNASMN1; SMN2 | |
| SCHEMBL7980939 | 0.75 | MAPT (0.54) | L3MBTL1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL11282223 | 0.74 | HTR1D (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |