Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | RB1 | P06400 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983973 | 0.87 | HTR1B (0.49) | HTR1DHTR1BAHR | |
| SCHEMBL7980657 | 0.86 | HTR1D (0.35) | HTR1DHTR1BHTR1AKIT | |
| SCHEMBL7980852 | 0.82 | MAPT (0.40) | — | |
| SCHEMBL7980653 | 0.82 | MAPT (0.40) | — | |
| SCHEMBL7977148 | 0.82 | MAPT (0.40) | — | |
| SCHEMBL7980655 | 0.81 | ADRB3 (0.44) | — | |
| SCHEMBL11418263 | 0.79 | MCHR1 (0.49) | — | |
| SCHEMBL7977557 | 0.79 | L3MBTL1 (0.47) | KIT | |
| SCHEMBL7111545 | 0.77 | MTNR1A (0.57) | HTR1DHTR1BHTR1A | |
| SCHEMBL6912027 | 0.76 | KIF11 (0.42) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |