SCHEMBL7977938

SCHEMBL7977938

C#CCN1C(=O)COc2ccc(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)nc21

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BCAT1 P54687 11/20 0.31
BCAT2 O15382 10/20 0.31
TERT O14746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9478291 0.81 BCAT1 (0.38) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL7978010 0.80 DRD2 (0.32) TERT
SCHEMBL7980627 0.80
SCHEMBL7977825 0.79 DRD2 (0.33)
SCHEMBL9427475 0.77 BCAT1 (0.41) ALDH1A1CYP2C9CYP2C19SMN1; SMN2BCAT1
SCHEMBL7964481 0.71 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7980643 0.70 TSHR (0.36) ALDH1A1
SCHEMBL6627299 0.67 BCAT1 (0.45) BCAT1BCAT2
SCHEMBL7977886 0.67 SLC5A1 (0.36) ALDH1A1CYP2C9TERT
SCHEMBL7964514 0.67 TSHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001030782-A2 NOVEL HERBICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-05-03 WO disclosed