Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | SCN1A | P35498 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302838 | 0.82 | HTT (0.70) | SIGMAR1HTTADRA1AHTR1AADRA1D | |
| SCHEMBL15529750 | 0.82 | HTT (0.75) | SIGMAR1HTTADRA1AHTR1AADRA1D | |
| SCHEMBL3333232 | 0.81 | SCN1A (0.53) | SIGMAR1HTTADRA1ASLC6A2SLC6A4 | |
| SCHEMBL7288351 | 0.81 | SCN1A (0.57) | SIGMAR1HTTADRA1AHTR1ASLC6A2 | |
| SCHEMBL7433830 | 0.78 | SLC6A2 (0.58) | SIGMAR1HTTADRA1AHTR1AADRA1D | |
| SCHEMBL4670218 | 0.76 | SCN1A (0.61) | SIGMAR1HTTADRA1ASLC6A2SLC6A4 | |
| SCHEMBL4669231 | 0.76 | SLC6A2 (0.61) | SIGMAR1HTTADRA1ASLC6A2SLC6A4 | |
| SCHEMBL4667564 | 0.76 | SCN1A (0.65) | SIGMAR1HTTADRA1AHTR1ASLC6A2 | |
| SCHEMBL3333230 | 0.76 | SIGMAR1 (0.68) | SIGMAR1HTTADRA1AHTR1AADRA1D | |
| Bromomethane SCHEMBL5569429 | 0.76 | SLC6A2 (0.56) | SIGMAR1HTTADRA1AHTR1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |