Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 6/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989957 | 0.87 | USP2 (0.48) | CHEK2DGAT1NOTUMLMNAMAPT | |
| SCHEMBL7991701 | 0.84 | MALT1 (0.41) | CHEK2DGAT1NOTUMLMNAMAPT | |
| SCHEMBL7991843 | 0.83 | AURKA (0.45) | CHEK2DGAT1LMNAMAPTKMT2A | |
| SCHEMBL7988137 | 0.82 | PRKAB2 (0.52) | CHEK2DGAT1LMNAMAPTKMT2A | |
| SCHEMBL7978156 | 0.82 | AKR1C3 (0.47) | CHEK2DGAT1LMNAMAPTKMT2A | |
| SCHEMBL7989662 | 0.82 | LMNA (0.45) | CHEK2DGAT1LMNAMAPTKMT2A | |
| SCHEMBL7977506 | 0.82 | PRKAB2 (0.43) | DGAT1KMT2ASMN1; SMN2PARP1PRKAB2 | |
| SCHEMBL7978074 | 0.82 | DGAT1 (0.40) | CHEK2DGAT1NOTUMLMNAMAPT | |
| SCHEMBL7991773 | 0.81 | PARP1 (0.51) | CHEK2LMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7991757 | 0.81 | DGAT1 (0.42) | CHEK2DGAT1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |