Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993029 | 0.94 | GPR84 (0.50) | GPR84GSK3BEIF2AK2CDK4CCND1 | |
| SCHEMBL7992854 | 0.82 | GPR84 (0.41) | GPR84KMT2AMEN1 | |
| SCHEMBL7978256 | 0.81 | HTR2A (0.43) | GPR84KMT2AMEN1HTR6HTR1A | |
| SCHEMBL7990994 | 0.81 | HTR2A (0.52) | KMT2AMEN1HTR1A | |
| SCHEMBL7992535 | 0.81 | PTGDR (0.50) | CDK2KMT2AMEN1HTR6 | |
| SCHEMBL7996376 | 0.79 | POLB (0.53) | KMT2APOLBHDAC3HDAC4HDAC1 | |
| SCHEMBL5390245 | 0.76 | PRKCA (0.43) | GPR84GSK3BCDK2KMT2APOLB | |
| SCHEMBL7989807 | 0.74 | CDC7 (0.39) | GPR84GSK3BKMT2AMEN1 | |
| SCHEMBL7996288 | 0.73 | MTNR1A (0.46) | GSK3B | |
| SCHEMBL8805136 | 0.72 | HTR2A (0.55) | KMT2APOLBSLC2A1RAD52HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |