Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967929 | 0.87 | LMNA (0.43) | GAALMNAMAPTTDP1KDM4E | |
| SCHEMBL7981111 | 0.81 | KDM4E (0.48) | GAALMNAMAPTTDP1KDM4E | |
| SCHEMBL7977861 | 0.80 | GAA (0.47) | GAAMAPTKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8029778 | 0.73 | ALDH1A1 (0.40) | GAAMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL7413629 | 0.71 | NPC1 (0.43) | VCAM1LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL2651319 | 0.71 | VCAM1 (0.46) | VCAM1LMNAMAPTKDM4ETHRB | |
| SCHEMBL4482654 | 0.71 | VCAM1 (0.53) | VCAM1GAALMNAMAPTALDH1A1 | |
| SCHEMBL4482651 | 0.71 | VCAM1 (0.53) | VCAM1GAALMNAMAPTALDH1A1 | |
| SCHEMBL15270960 | 0.70 | MEN1 (0.54) | VCAM1LMNAMAPTKDM4ETHRB | |
| SCHEMBL2646355 | 0.69 | KMT2A (0.47) | VCAM1LMNAMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |