Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967929 | 0.83 | LMNA (0.43) | ALDH1A1KDM4EHTTGAASMN1; SMN2 | |
| SCHEMBL8029767 | 0.83 | ALOX15 (0.43) | ALDH1A1KDM4EHTTPTGER4ALOX15 | |
| SCHEMBL7977861 | 0.77 | GAA (0.47) | ALDH1A1KDM4EHTTGAATSHR | |
| SCHEMBL7978452 | 0.73 | VCAM1 (0.46) | ALDH1A1KDM4EHTTGAARAB9A | |
| SCHEMBL7097430 | 0.72 | ALOX15 (0.35) | ALDH1A1KDM4EHTTPTGER4ALOX15 | |
| SCHEMBL7411883 | 0.72 | AAK1 (0.41) | PRKCI | |
| SCHEMBL7476265 | 0.72 | ALOX15 (0.36) | ALDH1A1KDM4EHTTPTGER4ALOX15 | |
| SCHEMBL408918 | 0.66 | PTGER4 (0.67) | ALDH1A1KDM4EHTTGAAPTGER4 | |
| SCHEMBL7981111 | 0.65 | KDM4E (0.48) | ALDH1A1KDM4EGAASMN1; SMN2HPGD | |
| SCHEMBL7981483 | 0.64 | PRKCI (0.39) | ALDH1A1HTTGAAPRKCISMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |