Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978452 | 0.81 | VCAM1 (0.46) | KDM4EMAPTMGLLMAPK1ALDH1A1 | |
| SCHEMBL7977861 | 0.77 | GAA (0.47) | KDM4EMAPTALDH1A1L3MBTL1GAA | |
| SCHEMBL7967929 | 0.76 | LMNA (0.43) | KDM4EMAPTMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL5205743 | 0.72 | PKM (0.45) | MAPTHPGDMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL18795102 | 0.72 | ALDH1A1 (0.44) | MAPTHPGDMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL4093917 | 0.70 | VCAM1 (0.45) | KDM4EMAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL10651912 | 0.69 | MAPT (0.43) | MAPTHPGDMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7061410 | 0.69 | ALDH1A1 (0.42) | MAPTHPGDMAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7868341 | 0.68 | MAPT (0.40) | MAPTHPGDALDH1A1L3MBTL1TDP1 | |
| SCHEMBL31245529 | 0.68 | HPGD (0.53) | MAPTHPGDALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |