Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 8/20 | 0.48 |
| ▸ | BCHE | P06276 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108541 | 0.83 | L3MBTL1 (0.60) | L3MBTL1MAPTMAOBLMNASMN1; SMN2 | |
| SCHEMBL5194103 | 0.81 | L3MBTL1 (0.59) | L3MBTL1MAPTMAOBTDP1LMNA | |
| SCHEMBL7977236 | 0.80 | L3MBTL1 (0.55) | L3MBTL1MAPTMAOBTDP1LMNA | |
| SCHEMBL7967629 | 0.80 | MAPT (0.55) | L3MBTL1MAPTMAOBTDP1LMNA | |
| SCHEMBL7980939 | 0.77 | MAPT (0.54) | L3MBTL1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7983419 | 0.75 | ALOX15 (0.52) | MAPTMAOBTDP1ACHEBCHE | |
| SCHEMBL3811564 | 0.74 | L3MBTL1 (0.80) | L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL20299180 | 0.74 | L3MBTL1 (0.79) | L3MBTL1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL7109712 | 0.73 | L3MBTL1 (0.60) | L3MBTL1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7110432 | 0.73 | L3MBTL1 (0.60) | L3MBTL1MAPTLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172099-B1 | CARBAZOLE, DIBENZOFURAN, OR DIBENZOTHIOPHENE DERIVATIVES; DIETETICS, ANTIDIABETIC AGENTS; ANTILIPEMICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0997458-A1 | NOVEL TRICYCLIC COMPOUNDS HAVING SATURATED RINGS AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 2000-05-03 | — | — | EP | disclosed |