Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140247 | 0.79 | ESR1 (0.42) | L3MBTL1GLA | |
| SCHEMBL7994197 | 0.73 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL7991696 | 0.71 | — | — | |
| SCHEMBL7993538 | 0.69 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL20267538 | 0.68 | PPOX (0.47) | L3MBTL1 | |
| SCHEMBL30537050 | 0.68 | PPOX (0.47) | L3MBTL1 | |
| SCHEMBL7955804 | 0.65 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL7251901 | 0.64 | L3MBTL1 (0.45) | L3MBTL1TSHRHSD17B10GLA | |
| SCHEMBL29238949 | 0.64 | NAPRT (0.49) | L3MBTL1ALDH1A1HPGDALOX15TSHR | |
| SCHEMBL21011975 | 0.63 | L3MBTL1 (0.42) | L3MBTL1ALDH1A1HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001090102-A2 | 6-HETEROCYCLYL-3-OXO-3,4-DIHYDRO-QUINOXALINES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-29 | — | — | WO | disclosed |