Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.56 |
| ▸ | CCR2 | P41597 | 6/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7067165 | 0.85 | PTGS1 (0.53) | PTGS2PTGS1PTGES2MEN1ALDH1A1 | |
| SCHEMBL7067226 | 0.84 | PTGS1 (0.53) | PTGS2PTGS1CCR2ITGB2ICAM1 | |
| SCHEMBL4575696 | 0.81 | PTGS1 (0.56) | PTGS2PTGS1CCR2ITGB2ICAM1 | |
| SCHEMBL7063649 | 0.79 | PTGS1 (0.48) | PTGS2PTGS1CCR2ITGB2ICAM1 | |
| SCHEMBL6598563 | 0.75 | PTGS1 (0.58) | PTGS2PTGS1CCR2ITGB2ICAM1 | |
| SCHEMBL8092090 | 0.75 | PTGS2 (0.44) | PTGS2PTGS1CCR2 | |
| SCHEMBL7066902 | 0.74 | PTGS1 (0.41) | PTGS2PTGS1ITGB2ICAM1ITGAL | |
| SCHEMBL8091883 | 0.72 | PTGS1 (0.44) | PTGS2PTGS1PTGES2 | |
| SCHEMBL9538398 | 0.72 | PTGS1 (0.55) | PTGS2PTGS1CCR2ITGB2ICAM1 | |
| SCHEMBL9539406 | 0.71 | PTGS1 (0.54) | PTGS2PTGS1CCR2ITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297282-B1 | TREATING INFLAMMATION AND PAIN | NYCOMED AUSTRIA GMBH (AT) | 2001-10-02 | — | — | US | disclosed |