Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1274798 | 0.75 | HSD11B1 (0.42) | — | |
| SCHEMBL7981007 | 0.72 | KMO (0.40) | CYP11B1CYP11B2 | |
| SCHEMBL19744126 | 0.70 | PDE3B (0.31) | — | |
| SCHEMBL1966360 | 0.69 | P2RX7 (0.36) | — | |
| SCHEMBL17514784 | 0.68 | — | — | |
| SCHEMBL17514789 | 0.67 | — | — | |
| SCHEMBL17514848 | 0.66 | — | — | |
| SCHEMBL17514918 | 0.66 | RAPGEF4 (0.30) | — | |
| SCHEMBL7803250 | 0.66 | KIF11 (0.41) | KIF11AHR | |
| SCHEMBL7967372 | 0.66 | KIF11 (0.49) | CYP11B1CYP11B2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432997-B1 | SYSTEMIC INSECTICIDES, NEMATOCIDES, LARVICIDES, MITICIDES, AND ANTHELMINTICS; AGRICULTURE, HORTICULTURE | RHONE-POULENC, INC. | 2002-08-13 | — | — | US | disclosed |