Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | YAP1 | P46937 | 2/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987630 | 0.89 | MEN1 (0.37) | MMP13LMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL16529459 | 0.84 | MMP13 (0.44) | MMP13CXCR2RENPTPN1 | |
| SCHEMBL7987575 | 0.82 | SCN9A (0.51) | PTPN1HDAC4HDAC1HDAC8HDAC6 | |
| SCHEMBL7984259 | 0.81 | TSHR (0.47) | TSHREPHX2 | |
| SCHEMBL7983863 | 0.79 | ALDH1A1 (0.43) | LMNATSHRALDH1A1CXCR2EPHX2 | |
| SCHEMBL7984913 | 0.77 | ALDH1A1 (0.47) | LMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL16529010 | 0.77 | CXCR2 (0.40) | MMP13CXCR2PTPN1 | |
| SCHEMBL7981994 | 0.76 | TSHR (0.37) | MMP13TSHRALDH1A1YAP1TEAD4 | |
| SCHEMBL31278485 | 0.76 | EPHX2 (0.46) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15566550 | 0.75 | KDM4E (0.45) | MMP13CXCR2RENPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | claimed |