SCHEMBL7987630

SCHEMBL7987630

CN(C(=O)OC(C)(C)C)[C@@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)c(OS(=O)(=O)C(F)(F)F)c1)C(=O)NC1CCCC1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MMP13 P45452 1/20 0.36
CTSD P07339 3/20 0.36
ALDH1A1 P00352 3/20 0.35
DRD2 P14416 1/20 0.35
DRD1 P21728 1/20 0.35
DRD4 P21917 1/20 0.35
DRD5 P21918 1/20 0.35
DRD3 P35462 1/20 0.35
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
LMNA P02545 2/20 0.34
EPHX1 P07099 1/20 0.34
TACR2 P21452 1/20 0.34
TACR1 P25103 1/20 0.34
TSHR P16473 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7981046 0.89 MMP13 (0.42) NPSR1MMP13ALDH1A1POLBSMN1; SMN2
SCHEMBL7981994 0.79 TSHR (0.37) MMP13CTSDALDH1A1DRD2POLB
SCHEMBL7984259 0.76 TSHR (0.47) CTSDDRD2EPHX1TSHRBACE1
SCHEMBL7987632 0.75 PTPN1 (0.46)
SCHEMBL16529459 0.73 MMP13 (0.44) MMP13
SCHEMBL7987575 0.72 SCN9A (0.51)
SCHEMBL7984913 0.69 ALDH1A1 (0.47) NPSR1CTSDALDH1A1SMN1; SMN2GAA
SCHEMBL7221311 0.69 KLK5 (0.49)
SCHEMBL29402224 0.69 ITGB3 (0.42) MMP13
SCHEMBL6927349 0.68 ITGB3 (0.46) KMT2AMMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US claimed