SCHEMBL7987575

SCHEMBL7987575

CC(C)(C)OC(=O)N[C@@H](Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1)C(=O)NC1CCCC1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 6/20 0.51
CTSS P25774 6/20 0.48
CTSK P43235 5/20 0.48
HDAC4 P56524 1/20 0.48
HDAC1 Q13547 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
BCL2 P10415 1/20 0.48
PTPN1 P18031 2/20 0.47
CTSL P07711 1/20 0.46
CTSB P07858 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
ITGB3 P05106 1/20 0.45
ITGA2B P08514 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7983863 0.86 ALDH1A1 (0.43)
SCHEMBL2847835 0.83 ITGB3 (0.61) CTSSCTSKBCL2PTPN1CTSL
SCHEMBL2853779 0.83 ITGB3 (0.61) CTSSCTSKBCL2PTPN1CTSL
SCHEMBL1932580 0.83 ITGB3 (0.61) CTSSCTSKBCL2PTPN1CTSL
SCHEMBL7981047 0.83 PTPN1 (0.51) CTSSCTSKBCL2PTPN1ITGB3
SCHEMBL2856829 0.82 ITGB3 (0.52) CTSSCTSKBCL2PTPN1CTSL
SCHEMBL2856826 0.82 ITGB3 (0.52) CTSSCTSKBCL2PTPN1CTSL
SCHEMBL18235378 0.82 ITGB3 (0.52) CTSSCTSKBCL2PTPN1CTSL
SCHEMBL7361331 0.82 BCL2 (0.61) SCN9ACTSSCTSKBCL2PTPN1
SCHEMBL7981046 0.82 MMP13 (0.42) HDAC4HDAC1HDAC6PTPN1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284912-B1 Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives LG CHEMICAL, LTD. (KR) 2001-09-04 US claimed