Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 18/20 | 0.57 |
| ▸ | PRKACA | P17612 | 10/20 | 0.57 |
| ▸ | PRKACG | P22612 | 10/20 | 0.57 |
| ▸ | PRKACB | P22694 | 10/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983756 | 0.76 | SRC (0.55) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7987642 | 0.75 | SRC (0.65) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981701 | 0.73 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7984055 | 0.68 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7980197 | 0.66 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7980199 | 0.64 | SRC (0.68) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7980223 | 0.64 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7981735 | 0.56 | SRC (1.00) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7969684 | 0.56 | SRC (1.00) | SRCPRKACAPRKACGPRKACBCA2 | |
| SCHEMBL15218462 | 0.56 | TSPO (0.40) | CA1CA2ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| EP-0586608-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER INC. (US) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |