Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 13/20 | 0.55 |
| ▸ | HTR1A | P08908 | 7/20 | 0.55 |
| ▸ | HTR2A | P28223 | 7/20 | 0.55 |
| ▸ | DRD2 | P14416 | 9/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989888 | 0.99 | DRD3 (0.54) | DRD3HTR1AHTR2ADRD2DRD4 | |
| SCHEMBL7986288 | 0.97 | DRD3 (0.51) | DRD3HTR1AHTR2ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7983890 | 0.96 | DRD3 (0.50) | DRD3HTR1AHTR2ADRD2DRD4 | |
| SCHEMBL7986218 | 0.89 | DRD3 (0.48) | DRD3HTR1AHTR2ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7983764 | 0.89 | DRD3 (0.47) | DRD3HTR1AHTR2ADRD2DRD4 | |
| SCHEMBL7989648 | 0.88 | SIGMAR1 (0.44) | DRD3HTR1AHTR2ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7972066 | 0.87 | SIGMAR1 (0.43) | DRD3HTR1AHTR2ADRD2DRD4 | |
| SCHEMBL7986609 | 0.86 | DRD3 (0.44) | DRD3 | |
| SCHEMBL7985583 | 0.86 | ALDH1A1 (0.43) | DRD4 | |
| SCHEMBL7982974 | 0.86 | ADRA1D (0.42) | DRD3HTR1AHTR2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |