Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539193 | 0.89 | MAPT (0.44) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL3142020 | 0.89 | ADRA2B (0.40) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL13813554 | 0.87 | ADRA2B (0.46) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL9754655 | 0.87 | KCNH3 (0.49) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL31548023 | 0.85 | LIPG (0.50) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL11213224 | 0.85 | LIPG (0.50) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL28170208 | 0.85 | MAPT (0.55) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL11609802 | 0.85 | LIPG (0.50) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL2493912 | 0.85 | LIPG (0.50) | MAPTGAATDP1KDM4EMEN1 | |
| SCHEMBL29657744 | 0.83 | MAPT (0.50) | MAPTGAATDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240565-A | A kind of preparation method of 9,9-dimethylacridan | 郑州原理生物科技有限公司 | 2019-09-17 | — | — | CN | claimed |
| CN-110240565-A | A kind of preparation method of 9,9-dimethylacridan | 郑州原理生物科技有限公司 | 2019-09-17 | — | — | CN | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-4362893-A | Preparation of C-nitrosodiarylamines from diarylamines | UOP INC. (US) | 1982-12-07 | — | — | US | disclosed |