SCHEMBL31405545

SCHEMBL31405545

ClC1=Nc2cc(Cl)cc(Cl)c21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
AHR P35869 1/20 0.39
TSHR P16473 5/20 0.38
HSD17B10 Q99714 3/20 0.38
CYP3A4 P08684 2/20 0.38
RECQL P46063 2/20 0.38
HPGD P15428 2/20 0.33
TP53 P04637 1/20 0.32
CES1 P23141 1/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30
NR1I2 O75469 1/20 0.30
SLC22A3 O75751 1/20 0.30
EGFR P00533 1/20 0.30
LMNA P02545 1/20 0.30
TTR P02766 1/20 0.30
ESR1 P03372 1/20 0.30
ERBB2 P04626 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2937097 0.69 TSHR (0.67) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL31405547 0.69 AKR1C4 (0.42) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL358001 0.60 ALDH1A1 (1.00) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL4458192 0.59 ALDH1A1 (0.59) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL4453597 0.59 AHR (0.68) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL5740853 0.58 ALDH1A1 (0.41) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL5494630 0.58 ALDH1A1 (0.41) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL8626365 0.58 ALDH1A1 (0.42) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL4452879 0.57 TSHR (0.50) ALDH1A1AHRTSHRHSD17B10CYP3A4
SCHEMBL4456478 0.57 ALDH1A1 (0.65) ALDH1A1AHRTSHRHSD17B10CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775103-B Resveratrol and preparation method and application thereof 湖南复瑞生物医药技术有限责任公司 2025-05-27 CN claimed
CN-119775103-A Resveratrol and preparation method and application thereof 湖南复瑞生物医药技术有限责任公司 2025-04-08 CN claimed
CN-119775103-B Resveratrol and preparation method and application thereof 湖南复瑞生物医药技术有限责任公司 2025-05-27 CN disclosed
CN-119775103-B Resveratrol and preparation method and application thereof 湖南复瑞生物医药技术有限责任公司 2025-05-27 CN disclosed
CN-119775103-A Resveratrol and preparation method and application thereof 湖南复瑞生物医药技术有限责任公司 2025-04-08 CN disclosed
CN-119775103-A Resveratrol and preparation method and application thereof 湖南复瑞生物医药技术有限责任公司 2025-04-08 CN disclosed