Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7639437 | 0.86 | ALDH1A1 (0.43) | KDM4EMAPK1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7676263 | 0.84 | LMNA (0.43) | KDM4ENPC1MITFRAB9ATHRB | |
| SCHEMBL6816478 | 0.79 | RORC (0.53) | KDM4ERORCALDH1A1KMT2AGAA | |
| SCHEMBL6815477 | 0.79 | RORC (0.53) | KDM4ERORCALDH1A1KMT2AGAA | |
| SCHEMBL7868199 | 0.72 | HPGD (0.56) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6814942 | 0.72 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL6814738 | 0.72 | ALDH1A1 (0.48) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6810869 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6816651 | 0.71 | KDM4E (0.52) | KDM4EALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL7165778 | 0.71 | KMT2A (0.52) | KDM4EALDH1A1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |