Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815576 | 0.85 | KDM4E (0.52) | LMNASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL7982336 | 0.84 | RXRA (0.39) | LMNAMAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7639437 | 0.83 | ALDH1A1 (0.43) | LMNAMAPK1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL6815477 | 0.80 | RORC (0.53) | LMNAHTTKDM4EMEN1KMT2A | |
| SCHEMBL6816478 | 0.80 | RORC (0.53) | LMNAHTTKDM4EMEN1KMT2A | |
| SCHEMBL6814925 | 0.79 | SMN1; SMN2 (0.44) | LMNAMAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7676258 | 0.78 | ALDH1A1 (0.61) | LMNAHTTKDM4EMEN1KMT2A | |
| SCHEMBL6814321 | 0.74 | KDM4E (0.41) | LMNAHTTRAB9ASMN1; SMN2PARP10 | |
| SCHEMBL7592688 | 0.74 | SMN1; SMN2 (0.49) | LMNAHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7938420 | 0.74 | RAB9A (0.45) | LMNANPC1RAB9AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407123-B1 | VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |