Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982385 | 0.90 | KIT (0.31) | — | |
| SCHEMBL7985365 | 0.88 | RORC (0.38) | GLAPOLBGAATSHRHSD11B1 | |
| SCHEMBL7978754 | 0.87 | HSD11B1 (0.35) | HSD11B1 | |
| SCHEMBL7968601 | 0.86 | ACSS2 (0.37) | — | |
| SCHEMBL1418638 | 0.85 | NSD2 (0.33) | — | |
| SCHEMBL7984625 | 0.83 | KDM4E (0.36) | — | |
| SCHEMBL7980163 | 0.83 | P2RX7 (0.36) | — | |
| SCHEMBL7978690 | 0.82 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL12671069 | 0.78 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL7988318 | 0.78 | RORC (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |