Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978690 | 0.92 | HSD11B1 (0.36) | KITKDM4ERAD52 | |
| SCHEMBL7980163 | 0.91 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL7978754 | 0.91 | HSD11B1 (0.35) | — | |
| SCHEMBL7982383 | 0.90 | GLA (0.37) | — | |
| SCHEMBL7988318 | 0.87 | RORC (0.40) | KITP2RX7 | |
| SCHEMBL7989327 | 0.87 | MAOB (0.32) | KDM4ERAD52 | |
| SCHEMBL7984625 | 0.87 | KDM4E (0.36) | KDM4E | |
| SCHEMBL7993122 | 0.86 | HSD11B1 (0.36) | KIT | |
| SCHEMBL1418314 | 0.85 | ACSS2 (0.39) | — | |
| SCHEMBL12671238 | 0.84 | PRKDC (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001946-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | アステラス製薬株式会社 (JP) | 2010-01-07 | — | — | WO | disclosed |