Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971528 | 0.85 | KMT2A (0.66) | SLC9A1CYP3A4CYP2C19ALDH1A1KMT2A | |
| SCHEMBL7985451 | 0.83 | ALDH1A1 (0.54) | SLC9A1CYP3A4CYP2C19ALDH1A1KMT2A | |
| Sabiporide SCHEMBL29385812 | 0.82 | SLC9A1 (0.70) | SLC9A1CYP3A4CYP2C19HPGDSNPY2R | |
| Sabiporide SCHEMBL1286662 | 0.82 | SLC9A1 (0.70) | SLC9A1CYP3A4CYP2C19HPGDSNPY2R | |
| SCHEMBL14491835 | 0.82 | SLC9A1 (0.85) | SLC9A1CYP3A4CYP2C19HPGDSNPY2R | |
| Sabiporide SCHEMBL1286663 | 0.82 | SLC9A1 (1.00) | SLC9A1CYP3A4CYP2C19 | |
| Sabiporide SCHEMBL1286645 | 0.81 | SLC9A1 (0.69) | SLC9A1CYP3A4CYP2C19HPGDSNPY2R | |
| SCHEMBL7985330 | 0.81 | NPY2R (0.57) | ALDH1A1KMT2ANPY2RRBP4 | |
| SCHEMBL7982517 | 0.81 | RBP4 (0.54) | SLC9A1CYP3A4CYP2C19ALDH1A1KMT2A | |
| Sabiporide SCHEMBL27472449 | 0.81 | SLC9A1 (0.89) | SLC9A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |