Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.57 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | RBP4 | P02753 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | PHGDH | O43175 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982517 | 0.90 | RBP4 (0.54) | NPY2RRBP4POLBLMNAHPGD | |
| SCHEMBL7971528 | 0.89 | KMT2A (0.66) | NPY2RRBP4POLBLMNAALDH1A1 | |
| SCHEMBL7985106 | 0.89 | NPY2R (0.56) | NPY2RRBP4LMNAHPGDALDH1A1 | |
| SCHEMBL7985451 | 0.85 | ALDH1A1 (0.54) | NPY2RRBP4LMNAHPGDALDH1A1 | |
| SCHEMBL7982405 | 0.82 | KMT2A (0.53) | NPY2RRBP4HPGDALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6137329 | 0.81 | NPY2R (0.51) | NPY2RRBP4POLBLMNAHPGD | |
| SCHEMBL7982477 | 0.81 | SLC9A1 (0.69) | NPY2RRBP4ALDH1A1KMT2A | |
| SCHEMBL7985104 | 0.80 | TSHR (0.58) | NPY2RPOLBLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7971257 | 0.80 | ALDH1A1 (0.59) | RBP4POLBLMNAHPGDALDH1A1 | |
| SCHEMBL4278043 | 0.80 | WDR5 (0.52) | RBP4HPGDALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |