Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971528 | 0.91 | KMT2A (0.66) | ALDH1A1KMT2AMEN1NPY2RMAPT | |
| SCHEMBL7982405 | 0.86 | KMT2A (0.53) | ALDH1A1KMT2AMEN1NPY2RMAPT | |
| SCHEMBL7985330 | 0.85 | NPY2R (0.57) | ALDH1A1KMT2AMEN1NPY2RMAPT | |
| SCHEMBL7982517 | 0.85 | RBP4 (0.54) | ALDH1A1KMT2ANPY2RLMNAHTT | |
| SCHEMBL7985106 | 0.84 | NPY2R (0.56) | ALDH1A1KMT2AMEN1NPY2RMAPT | |
| SCHEMBL7985104 | 0.84 | TSHR (0.58) | ALDH1A1KMT2AMEN1NPY2RMAPT | |
| SCHEMBL4278043 | 0.83 | WDR5 (0.52) | ALDH1A1MAPTHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL1480130 | 0.83 | NOTUM (0.46) | ALDH1A1KMT2AMEN1NPY2RMAPT | |
| SCHEMBL7982477 | 0.83 | SLC9A1 (0.69) | ALDH1A1KMT2ANPY2RRBP4CYP3A4 | |
| SCHEMBL7971257 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323207-B1 | TREATMENT OR REDUCTION OF TISSUE DAMAGE DUE TO ISCHAEMIA WHICH COMPRISES ADMINISTERING TO A HOST SUFFERING FROM ISCHAEMIA | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-11-27 | — | — | US | disclosed |