Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 4/20 | 0.48 |
| ▸ | ACE | P12821 | 6/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983227 | 0.86 | MMP1 (0.54) | MMEMMP1FCER2MMP2MMP9 | |
| SCHEMBL7068105 | 0.86 | EPHX2 (0.47) | MMELMNA | |
| SCHEMBL7066970 | 0.81 | LTA4H (0.41) | MMEACEMMP1POLBLMNA | |
| SCHEMBL7135106 | 0.78 | ACE (0.49) | MMEACEECE1MMP1FCER2 | |
| SCHEMBL7983204 | 0.76 | MMP1 (0.58) | MMEACEMMP1FCER2PSMB5 | |
| SCHEMBL7983199 | 0.76 | MMP1 (0.58) | MMEACEMMP1FCER2PSMB5 | |
| SCHEMBL7128547 | 0.74 | MME (0.51) | MMEACE | |
| SCHEMBL7128546 | 0.74 | MME (0.51) | MMEACE | |
| SCHEMBL7982631 | 0.72 | EPHX2 (0.48) | MMEACEALDH1A1 | |
| SCHEMBL10662363 | 0.70 | ACE (0.63) | MMEACEECE1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060161-B1 | MATRIX METALLOPROTEINASE INHIBITORS | LEO PHARMA AS WITH SECONDARY N (DK) | 2003-06-11 | — | — | EP | disclosed |