Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK2 | P53671 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981738 | 0.84 | KDM4E (0.55) | KDM4EPKM | |
| SCHEMBL7987167 | 0.84 | KDM4E (0.45) | GPR119KDM4EPKM | |
| SCHEMBL7981945 | 0.82 | KDM4E (0.44) | GPR119KDM4EPKM | |
| SCHEMBL7983168 | 0.78 | FAAH (0.40) | GPR119KDM4EPKM | |
| SCHEMBL7983171 | 0.78 | FAAH (0.40) | GPR119KDM4EPKM | |
| SCHEMBL7973179 | 0.78 | GPR119 (0.39) | GPR119KDM4EPKM | |
| SCHEMBL7989480 | 0.78 | KDM4E (0.47) | GPR119KDM4EPKM | |
| SCHEMBL7989477 | 0.78 | KDM4E (0.47) | GPR119KDM4EPKM | |
| SCHEMBL7973184 | 0.78 | GPR119 (0.39) | GPR119KDM4EPKM | |
| SCHEMBL7987858 | 0.76 | TGFBR1 (0.44) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |