Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.55 |
| ▸ | DRD3 | P35462 | 5/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983134 | 0.96 | HTR7 (0.57) | HTR7DRD3HTR1ADRD2HRH1 | |
| SCHEMBL8667745 | 0.81 | WEE1 (0.40) | HTR7DRD3HTR1ADRD2HRH1 | |
| SCHEMBL7986389 | 0.79 | CCR3 (0.50) | — | |
| SCHEMBL7986154 | 0.79 | HTR1A (0.53) | HTR7DRD3HTR1ADRD2 | |
| SCHEMBL8557009 | 0.78 | CHEK1 (0.47) | HTR2A | |
| SCHEMBL3174237 | 0.78 | CHEK1 (0.47) | DRD3DRD2HRH1HTR2A | |
| SCHEMBL7989675 | 0.77 | SIGMAR1 (0.54) | HTR7DRD2 | |
| SCHEMBL8554507 | 0.77 | SIGMAR1 (0.47) | HRH1HTR2A | |
| SCHEMBL23142609 | 0.76 | CCNE2 (0.43) | — | |
| SCHEMBL4910767 | 0.76 | CHEK1 (0.50) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |