Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | PRKACG | P22612 | 1/20 | 0.55 |
| ▸ | PRKACB | P22694 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987262 | 0.87 | SRC (0.50) | SRCPRKACAPRKACGPRKACBNPC1 | |
| SCHEMBL7988065 | 0.85 | SRC (0.54) | SRCPRKACAPRKACGPRKACBNPC1 | |
| SCHEMBL7971057 | 0.83 | SRC (0.52) | SRCPRKACAPRKACGPRKACBNPC1 | |
| SCHEMBL7981595 | 0.82 | SRC (0.55) | SRCPRKACAPRKACGPRKACBNPC1 | |
| SCHEMBL7970249 | 0.80 | SRC (0.57) | SRCPRKACAPRKACGPRKACB | |
| SCHEMBL7983604 | 0.79 | SRC (0.58) | SRCPRKACAPRKACGPRKACBRAB9A | |
| SCHEMBL7970472 | 0.73 | SRC (0.55) | SRCPRKACAPRKACGPRKACBNPC1 | |
| SCHEMBL7981392 | 0.72 | SRC (0.61) | SRCNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL5074187 | 0.68 | CYP1A2 (0.73) | NPC1RAB9AAKR1C3NQO2CASP3 | |
| SCHEMBL8499452 | 0.68 | CYP1A2 (0.73) | NPC1RAB9AAKR1C3NQO2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194439-B1 | ANTICANCER AGENT | PFIZER INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1992021660-A1 | TRICYCLIC POLYHYDROXYLIC TYROSINE KINASE INHIBITORS | PFIZER, INC. (US) | 1992-12-10 | — | — | WO | disclosed |