Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.47 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.47 |
| ▸ | PARN | O95453 | 1/20 | 0.46 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984934 | 0.90 | CNOT7 (0.47) | ABCC8KCNJ11PARNCNOT7TNKS | |
| SCHEMBL7988524 | 0.90 | ABCC8 (0.47) | ABCC8KCNJ11PARNCNOT7TNKS | |
| SCHEMBL7987364 | 0.89 | TNKS (0.46) | ABCC8KCNJ11PARNCNOT7TNKS | |
| SCHEMBL7987953 | 0.89 | PDE2A (0.46) | PARNCNOT7TNKSTNKS2SMN1; SMN2 | |
| SCHEMBL7985012 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11PARNCNOT7NR1H4 | |
| SCHEMBL7991403 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11PARNCNOT7NR1H4 | |
| SCHEMBL7974239 | 0.89 | CNOT7 (0.45) | ABCC8KCNJ11PARNCNOT7NR1H4 | |
| SCHEMBL7975271 | 0.89 | CNOT7 (0.56) | PARNCNOT7SMN1; SMN2ADORA2BRXFP1 | |
| SCHEMBL7984871 | 0.89 | ABCC8 (0.45) | ABCC8KCNJ11PARNCNOT7TNKS | |
| SCHEMBL8056964 | 0.88 | CNOT7 (0.47) | ABCC8KCNJ11PARNCNOT7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |