Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RGS12 | O14924 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976612 | 0.85 | GAA (0.60) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2976618 | 0.85 | GAA (0.60) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9521629 | 0.82 | ALDH1A1 (0.47) | GAACYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL6990630 | 0.82 | LMNA (0.58) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6464717 | 0.81 | PDE4A (0.47) | GAACYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL6464728 | 0.81 | PDE4A (0.47) | GAACYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL1865824 | 0.80 | CASP6 (0.55) | GAACYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL10410167 | 0.80 | CTSV (0.59) | MEN1KMT2AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL11680950 | 0.79 | MEN1 (0.45) | GAACYP1A2MEN1KMT2AALDH1A1 | |
| SCHEMBL11680122 | 0.79 | MEN1 (0.51) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055139-A1 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |