Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984299 | 1.00 | PLA2G7 (0.41) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL7985329 | 0.82 | MMP1 (0.43) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL7984296 | 0.76 | NFE2L2 (0.34) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL7985258 | 0.68 | PLA2G7 (0.36) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL4827863 | 0.67 | PLA2G7 (0.46) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL6950299 | 0.65 | PLA2G7 (0.42) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL7603860 | 0.63 | PLA2G7 (0.40) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL6952582 | 0.60 | MMP2 (0.38) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL6945448 | 0.60 | MMP2 (0.39) | PLA2G7MMP2MMP1MMP3MMP9 | |
| SCHEMBL11640023 | 0.60 | KMT2A (0.50) | PLA2G7MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274758-B1 | ENANTIOMORPH SELECTIVITY | DARWIN DISCOVERY, LTD. (GB) | 2001-08-14 | — | — | US | disclosed |