Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984290 | 1.00 | NFE2L2 (0.34) | NFE2L2KCNH2PLA2G7HTR6ITGAV | |
| SCHEMBL7984293 | 0.76 | PLA2G7 (0.41) | NFE2L2KCNH2PLA2G7HTR6ALDH1A1 | |
| SCHEMBL7984299 | 0.76 | PLA2G7 (0.41) | NFE2L2KCNH2PLA2G7HTR6ALDH1A1 | |
| SCHEMBL6370065 | 0.59 | HSD17B10 (0.41) | PLA2G7ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL5248910 | 0.57 | HTR6 (0.55) | NFE2L2KCNH2HTR6KMT2A | |
| SCHEMBL28547097 | 0.56 | HTR6 (0.54) | HTR6ITGAVKMT2ASMN1; SMN2MMP2 | |
| SCHEMBL28047937 | 0.56 | NFE2L2 (0.54) | NFE2L2KCNH2HTR6KMT2A | |
| SCHEMBL13370774 | 0.56 | HTR6 (0.58) | NFE2L2KCNH2HTR6KDM4EKMT2A | |
| SCHEMBL14676509 | 0.56 | ITGAV (0.46) | HTR6ITGAVALDH1A1SMN1; SMN2 | |
| SCHEMBL8713487 | 0.56 | HTR6 (0.53) | NFE2L2KCNH2HTR6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6274758-B1 | ENANTIOMORPH SELECTIVITY | DARWIN DISCOVERY, LTD. (GB) | 2001-08-14 | — | — | US | disclosed |