Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | GNRHR | P30968 | 2/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985012 | 0.90 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7974282 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7992270 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7984427 | 0.89 | HPGD (0.44) | CNOT7PARNPNPKDM4ENPC1 | |
| SCHEMBL7974492 | 0.89 | ABCC8 (0.47) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7988017 | 0.89 | KDM4E (0.43) | ABCC8KCNJ11KDM4ENPC1ALDH1A1 | |
| SCHEMBL7984474 | 0.89 | ABCC8 (0.42) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7988524 | 0.88 | ABCC8 (0.47) | ABCC8KCNJ11NR1H4CNOT7PARN | |
| SCHEMBL7984663 | 0.88 | CNOT7 (0.49) | CNOT7PARNPNPKDM4ENPC1 | |
| SCHEMBL7985602 | 0.88 | SERPINE1 (0.45) | ABCC8KCNJ11TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |