Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 4/20 | 0.39 |
| ▸ | BECN1 | Q14457 | 2/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984761 | 0.90 | CYP17A1 (0.42) | ADORA3CYP17A1HPGDP2RX7CDK9 | |
| SCHEMBL7974458 | 0.82 | ADORA2A (0.44) | ADORA3HPGDSLC2A1ADORA2BALDH1A1 | |
| SCHEMBL7984479 | 0.82 | HPGD (0.52) | CYP17A1PTGDR2MAPKAPK2HPGDP2RX7 | |
| SCHEMBL7975267 | 0.79 | SMN1; SMN2 (0.46) | ADORA3HPGDADORA2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7988558 | 0.78 | SMN1; SMN2 (0.43) | ADORA3HPGDALDH1A1SMN1; SMN2ADORA2A | |
| SCHEMBL7985225 | 0.78 | GAA (0.48) | ADORA3HPGDP2RX7ADORA2BALDH1A1 | |
| SCHEMBL7975133 | 0.78 | ADORA2A (0.50) | ADORA3HPGDALDH1A1SMN1; SMN2ADORA2A | |
| SCHEMBL7991662 | 0.77 | HPGD (0.41) | HPGDP2RX7CDK9ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984489 | 0.77 | P2RX7 (0.45) | CYP17A1PTGDR2MAPKAPK2HPGDP2RX7 | |
| SCHEMBL7974156 | 0.77 | BRD4 (0.43) | ADORA3HPGDSLC2A1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |