Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
| ▸ | PARN | O95453 | 1/20 | 0.44 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984762 | 0.90 | P2RX7 (0.45) | P2RX7PARNCNOT7CYP17A1HPGD | |
| SCHEMBL7984479 | 0.86 | HPGD (0.52) | P2RX7PARNCNOT7CYP17A1PTGDR2 | |
| SCHEMBL7985482 | 0.84 | PAX8 (0.43) | P2RX7PARNCNOT7HPGDALDH1A1 | |
| SCHEMBL7974461 | 0.82 | CNOT7 (0.49) | PARNCNOT7HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7975271 | 0.81 | CNOT7 (0.56) | PARNCNOT7HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7988562 | 0.80 | CNOT7 (0.54) | PARNCNOT7HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7985228 | 0.80 | CXCR2 (0.50) | P2RX7PARNCNOT7HPGDALDH1A1 | |
| SCHEMBL7984461 | 0.79 | CNOT7 (0.52) | PARNCNOT7HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7975135 | 0.79 | CNOT7 (0.52) | PARNCNOT7HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7974480 | 0.79 | GUSB (0.50) | P2RX7PARNCNOT7HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |