Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PARN | O95453 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984759 | 0.91 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1KMT2AP2RX7 | |
| SCHEMBL7984489 | 0.86 | P2RX7 (0.45) | HPGDSMN1; SMN2ALDH1A1P2RX7CYP17A1 | |
| SCHEMBL7985473 | 0.83 | HPGD (0.49) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7974456 | 0.83 | SMN1; SMN2 (0.55) | HPGDSMN1; SMN2ALDH1A1KMT2APARN | |
| SCHEMBL7984487 | 0.82 | ADORA3 (0.43) | HPGDSMN1; SMN2ALDH1A1P2RX7CYP17A1 | |
| SCHEMBL7975265 | 0.80 | SMN1; SMN2 (0.61) | HPGDSMN1; SMN2ALDH1A1KMT2APARN | |
| SCHEMBL7991429 | 0.80 | HPGD (0.55) | HPGDSMN1; SMN2ALDH1A1KMT2AP2RX7 | |
| SCHEMBL7988556 | 0.80 | SMN1; SMN2 (0.58) | HPGDSMN1; SMN2ALDH1A1KMT2APARN | |
| SCHEMBL7985230 | 0.79 | ALDH1A1 (0.53) | HPGDSMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7984453 | 0.78 | ALDH1A1 (0.56) | HPGDSMN1; SMN2ALDH1A1KMT2APARN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |