Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | PARN | O95453 | 1/20 | 0.40 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985002 | 0.90 | ADORA2B (0.48) | ADORA2BADORA3ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7988254 | 0.87 | ADORA2B (0.50) | ADORA2BADORA3ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL7985382 | 0.86 | ADORA2B (0.46) | ADORA2BALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7984499 | 0.86 | ADORA2A (0.43) | ADORA2BADORA3ALDH1A1ADORA1ADORA2A | |
| SCHEMBL7975271 | 0.85 | CNOT7 (0.56) | ADORA2BADORA3BRD4ALDH1A1HPGD | |
| SCHEMBL7974067 | 0.85 | ADORA2B (0.46) | ADORA2BALDH1A1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL7974620 | 0.83 | CNOT7 (0.58) | ADORA2BALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL7984720 | 0.83 | CNOT7 (0.48) | ADORA2BADORA3ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7984791 | 0.83 | SMN1; SMN2 (0.45) | ALDH1A1CYP3A4TSHRPARNCNOT7 | |
| SCHEMBL7991406 | 0.81 | CNOT7 (0.49) | ALDH1A1HPGDMAPK1PARNCNOT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |