Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982606 | 0.99 | FAAH (0.39) | SIGMAR1FAAHNPC1HTTRAB9A | |
| SCHEMBL7985583 | 0.96 | ALDH1A1 (0.43) | SIGMAR1FAAHNPC1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL7983892 | 0.95 | ALDH1A1 (0.42) | SIGMAR1FAAHNPC1HTTRAB9A | |
| SCHEMBL7987161 | 0.94 | SMYD2 (0.42) | SIGMAR1FAAHNPC1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL7971940 | 0.93 | SMYD2 (0.41) | SIGMAR1FAAHNPC1HTTRAB9A | |
| SCHEMBL7984736 | 0.90 | SMYD2 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL7989522 | 0.90 | CHRM4 (0.53) | DRD4CHRM4 | |
| Hydrochloric Acid SCHEMBL7981574 | 0.90 | SMYD2 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL7973164 | 0.90 | SIGMAR1 (0.49) | SIGMAR1FAAHALDH1A1KDM4EALOX15 | |
| SCHEMBL7986609 | 0.89 | DRD3 (0.44) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |