Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984479 | 0.91 | HPGD (0.52) | HPGDALDH1A1SMN1; SMN2KMT2AP2RX7 | |
| SCHEMBL7984762 | 0.87 | P2RX7 (0.45) | HPGDALDH1A1SMN1; SMN2KMT2AP2RX7 | |
| SCHEMBL7974542 | 0.84 | SMN1; SMN2 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7984761 | 0.83 | CYP17A1 (0.42) | HPGDP2RX7TLR7MAPTGAA | |
| SCHEMBL7974152 | 0.82 | HPGD (0.47) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7985332 | 0.79 | SMN1; SMN2 (0.55) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7988590 | 0.79 | ALDH1A1 (0.53) | HPGDALDH1A1SMN1; SMN2KMT2AMAPT | |
| SCHEMBL7975265 | 0.78 | SMN1; SMN2 (0.61) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7974583 | 0.78 | GAA (0.59) | HPGDALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL7984466 | 0.78 | HPGD (0.42) | HPGDALDH1A1SMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |